Here is a great, brief article on the blood VFX from Assassin’s Creed 3. I’ve seen some similar effects demonstrated here, and thought this may be of interest, since they break it down quite well in the article.
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Is there a way to get the smooth threshold map in Photoshop rather than Substance Designer?
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You could always use the Maximum and Minimum filters, smudge the texture manually or with a blur filter, then layer it with the original input, and then use the Threshold and / or Levels adjustment layers to check if it’s looking great!
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Hey! I’m really glad you like the breakdown 
@OgnjenIlkic there is a video showing a similar technique in Photoshop by the amazing @Pete_Clark:
Photoshop threshold map
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Hey thanks, cool trick 
I can’t manage to get the more natural version of the texture without handpainting it.
https://cdn.80.lv/80.lv/uploads/2019/06/06_threshold_01.jpg
Any clues on how to achive this with filters etc.?
Filters like the “Dry Brush” will be your friends
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Hey thanks, nice breakdown.
Could you see the shader used?
Sorry, I cannot share that as we use proprietary tech and we are not allowed. I hope you understand 
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Yes, I understand, no problem