Remember your claaaaamps dude. Every time you are multiplying those textures together, the black values are also multiplying. Your current alpha values are probably around -2 - +4 or something. Rather than 0-1. You generally dont want values above or below 0-1 in alpha.
Like Travis mentioned it also looks like your alpha textures are scrolling at vastly different speeds. Id also go down to just two textures scrolling if I were you. It can be quite hard to work with 3 as the noise gets a little out of hand. I only use 3 noises if im creating a super large effect. Another tip if your trying to do fire. Have your v coordinates stretched. So say you have two texture noise samples. Have the V coordinate tiled at 0.5 and 1, rather than squared as they seem to be now.
Another tip with noise textures is to try keep your value ranges very wide. It looks like you have a lot of value crunched around the 0.5 area. This creates a very flat scrolling noise look.
Also try spawning your particles in a cylinder to see if its working. Its hard to see if they have different tiling when all of them are spawning on one another. You will mostly just see the static mask which is not moving in your current set up.