Hello!
The biggest thing that jumps off to me right off the bat is the camera movement. It seems you’re trying to do some time dilation/slow-mo thing along with camera shake. I don’t think it works well, especially with the slow-mo. It moves in a very large arc and makes it difficult to focus on the effect at the start.
Also might want to read another critique I did
I would suggest looking at real explosions and figuring out how they work.
What kind of explosion is it? A grenade? A molotov? A missile? Context! What’s combusting? What’s exploding? Where is the debris coming from?
Also maybe you should have different emitters and materials for your smoke. I can see the fire stepping in even at the very spaced apart billboards near the end and it really breaks the effect for me.
Secondary elements
The explosion just…happens. There is no anticipation. Try adding a few smaller explosions before the main one, and maybe some even smaller ones post the main explosion to curve it off. Or lob a grenade in there! Make it look more natural and feel more punchy and satisfying.
I know the point of this was to do the explosion effect, but making it interact with your world would add a lot to sell it. Burn the ground, destroy the house, smoke it up!
Good luck!